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KMID : 1100720200400060439
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Annals of Laboratory Medicine
2020 Volume.40 No. 6 p.439 ~ p.447
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COVID-19 Molecular Testing in Korea: Practical Essentials and Answers From Experts Based on Experiences of Emergency Use Authorization Assays
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Sung Heung-Sup
Roh Kyoung-Ho
Hong Ki-Ho
Seong Moon-Woo
Ryoo Nam-Hee
Kim Hyun-Soo
Lee Jae-Hyeon
Kim So-Yeon
Yoo Soo-Kwon
Kim Mi-Na
Han Myung-Guk
Lee Sang-Won
Lee Hyuk-Min
Yoo Cheon-Kwon
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Abstract
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Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Early detection of COVID-19 and immediate isolation of infected patients from the naive population are important to prevent further pandemic spread of the infection. Real-time reverse transcription (RT)-PCR to detect SARS-CoV-2 RNA is currently the most reliable diagnostic method for confirming COVID-19 worldwide. Guidelines for clinical laboratories on the COVID-19 diagnosis have been recently published by Korean Society for Laboratory Medicine and the Korea Centers for Disease Control and Prevention. However, these formal guidelines do not address common practical laboratory issues related to COVID-19 real-time RT-PCR testing and their solutions. Therefore, this guideline is intended as a practical and technical supplement to the “Guidelines for Laboratory Diagnosis of COVID-19 in Korea”.
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KEYWORD
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Coronavirus disease 2019, Laboratory diagnosis, Real-time RT-PCR, Guidelines, Korea
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